Provided is a wire harness shield structure with which it is possible to reduce the number of components. A shield structure for a circumstance wherein a wire (1) is introduced while being shielded within a shield wall (50) comprises a conductive rubber seal member (5), further comprising wire through holes (5a) through which it is possible to pass the wire (1) while said wire (1) is sealed, said rubber seal member (5) being mounted in a tightly fitting state on the shield wall (50). The wire (1) has a structure wherein an insulating resin layer (3) is formed on the exterior circumference of a conductor (2), and a shield layer (4) is coated by resin plating so as to encase the exterior circumference face of the insulating resin layer (3). By terminal parts of the wire (1) being passed through the wire through holes (5a) of the seal member (5) and inserted into the shield wall (50) up to the position of the shield layer (4), the inner circumferences of the wire through holes (5a) of the seal member (5) are tightly fitted to the shield layer (4), and the shield layer (4) and the conductive rubber seal member (5) are mutually interconnected.