The invention relates to a process for fabricating a medical fabric. The process is characterized by mainly comprising the following steps: (1) preparing a lining, wherein the lining is a blended fabric of natural cotton, spandex and polyester, and the fabric is a warp knitting fabric; (2) preparing a surface layer, wherein the main raw material of the surface layer is thermoplastic polyurethane, and quantitative silver nanoparticles are contained in the surface layer; (3) laminating the fabric, cladding the prepared surface layer film to the lining fabric, polyvinyl chloride (PVC) viscose is coated between the two fabric layers, and heating and pressurizing; and (4) performing hot-pressing molding, regulating the temperature of a drying oven to be 40-50 DEG C, wherein the baking time is 2 hours. The preparation process is reasonable in process arrangement and easy to implement, the double-layer fabric is high in adhesive strength, soft in texture and excellent in thermal insulation properties, and the unique antimicrobial efficacy has a good protective effect on medical workers, so that the medical workers can be safer and more comfortable in an operating environment.