A comprehensive assessment method for running of an intelligent power distribution network includes the steps of firstly, building a comprehensive assessment index system according to the running characteristic of the intelligent power distribution network; secondly, defining application range of the assessment method in terms of preference information, quantity of plans and relation between the quantity of plans and the quantity of attributes on the basis of investigation of the conventional comprehensive assessment method for the power distribution network, selecting the analytic hierarchy process, the fuzzy comprehensive evaluation method and the Delphi method as theoretical supports for comprehensive assessment according to real condition of assessment of running of the intelligent power distribution network, and on the basis of the three methods, providing comprehensive assessment methods and processes which include important links such as weight setting, scoring standard setting and assessment result analyzing. The comprehensive assessment index system relates to five indexes of safety, reliability, economy, high quality and intellectuality. The comprehensive assessment method has high practicability, feasibility and promotion and application value, and can provide important basis for scheduling and planning of the power distribution network and for management staff to make decision.