The invention discloses a large-dimension staged fracturing experiment simulation wellbore. The large-dimension staged fracturing experiment simulation wellbore comprises standard wellbore bodies, a first section wellbore body, a side cover, and an end cover, one end of each standard wellbore body is a male joint, the other end is a female joint, one side of the wellbore body is provided with an opening, the other side is provided with an arc slit, the slit is communicated with a liquid-injection pipeline joint via a liquid-injection hole, one end of the first section wellbore body is a female joint, the other end is a wellbore outlet without threads, the side cover is a thin-wall semicircular pipe, and one end of the end cover is provided with outside threads. One set of the large-dimension staged fracturing experiment simulation wellbore comprises one first section wellbore body, one end cover, and a plurality of standard wellbore bodies, and each wellbore body is connected with a hydraulic pump via an independent liquid-injection pipeline. The large-dimension staged fracturing experiment simulation wellbore is applicable to large-dimension staged hydraulic fracturing experiment simulation, the form of the slit in the experiment condition is obtained, the modular design is employed, the structure is simple, the operation is convenient, and the indoor experiment requirement can be met.