A power management system controlling power for a plurality of functional blocks included in a system-on-chip includes a plurality of programmable nano controllers, an instruction memory and a signal map memory. The instruction memory is shared by the nano controllers and stores a plurality of instructions that are used by the nano controllers. The signal map memory is shared by the nano controllers and stores a plurality of signals that are provided to the functional blocks and are controlled by the nano controllers. A first nano controller among the plurality of nano controllers is programmed as a central sequencer. Second through n-th nano controllers among the plurality of nano controllers are programmed as first sub-sequencers that are dependent on the first nano controller.