The invention provides a polypeptide having lipase activity, wherein the polypeptide has an amino acid sequence as shown in SEQ ID NO: 1 or a sequence including at least one substituted, deleted or added amino acid in the sequence. The invention also provides polynucleotide for coding the polypeptide, an expression vector and a host cell including the polynucleotide, and a method for producing the polypeptide. In addition, the invention also relates to application of the polypeptide having the lipase activity.