The invention discloses an ultrasonic extraction method of total alkaloids in Mongolian medicine fringed pinks. According to the ultrasonic extraction method, optimum extraction technological conditions are characterized in that ultrasonic temperature is 53 DEG C, a ratio of material to liquid is 31(g/mL), ultrasonic time is 41 minutes, and ultrasonic power is 140W. The ultrasonic extraction method of total alkaloids in the Mongolian medicine pinks is carried out according to the extraction technological conditions, and a recovery rate of total alkaloids can reach 3.085 mg/g. The content of total alkaloids extracted by the method is high, a large amount of time and solvent can be saved, and the ultrasonic extraction method provides a novel approach and a novel method for developing new drugs and using resource in a reasonable mode.