The invention provides a method and a device for quickly starting application programs of an intelligent POS (point-of-sale) machine. The method for quickly starting the application programs of the intelligent POS machine comprises steps as follows: step A: an opening path of an application program trigger instruction is established; step B: an application program is selected from the application programs of the POS machine and is set to be a trigger instruction application program; step C: interfaces of the intelligent POS machine are switched, and when any of the two sides of the interfaces is switched or any of two ends of the interfaces is triggered, the trigger instrument application program is started through the opening path. The device for quickly starting the application programs of the intelligent POS machine comprises at least two interfaces, a database system, a setting module and a starting module, wherein the database system is connected with at least one interface, the setting module and the starting module. The method and the device have the advantage that negative influences on consumers and commercial tenants are reduced.