The invention provides special multi-vitamin premix feed for grass carp liver care. The feed takes vitamins as a main component, and traditional Chinese herbal medicine is compounded for synergy. Reasonable compounding is carried out on the vitamins for solving the problem of hepatic and gall diseases of grass carps caused by long-term feed feeding during cultivation, and proved by experiments, by the premix feed, the morbidity of hepatic and gall diseases of the grass carps can be remarkably reduced, the survival rate in the cultivation is improved, and the income for the cultivation is increased.