The invention discloses an air purification system adopting wet dust removal. The air purification system comprises an air return channel, an electric induction device, a spray device, an air inlet filter unit and an electrostatic dust removal device, wherein the electric induction device is arranged on the indoor top, the inlet end of the electric induction device communicates with the air return channel, and a high-voltage negative power supply is arranged in the electric induction device; the inlet end of the spray device communicates with the outlet end of the electric induction device, and an air cleaning agent is arranged in the spray device; the outlet end of the air inlet filter unit is arranged on one side of the outlet end of the spray device, and the inlet end of the air inlet filter unit communicates with an air inlet of an air conditioning system; and the inlet end of the electrostatic dust removal device is arranged on the other side of the outlet end of the spray device, and the outlet end of the electrostatic dust removal device communicates with the indoor top space. According to the air purification system, the technical problems of poor dust removal effect of the air purification system and difficulty in increasing the quality of indoor air are solved.