The invention provides a clamp rotary positioning device and a curing device comprising the clamp rotary positioning device. The clamp rotary positioning device comprises an installation table, at least two clamps, a rotating assembly and a driving part. The clamps are arranged on the installation table side by side. The rotating assembly is connected with each of the clamps, and the rotating assembly drives each clamp to rotate. The drive part makes the rotating assembly rotate. By means of the clamp rotary positioning device, multiple medical accessories can be cured in multiple directions, the multiple medical accessories can be subjected to synchronous rotary positioning, and the work efficiency is obviously improved.