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Invention Publication
CN106232587A 式[I]中，RA为下式(A-1)表示的基团等，式(A-1)新型二取代1，2，4-三嗪化合物 中，环A1为可被取代的环烷基等；RB为单环式环 有权

式[I]中，RA为下式(A-1)表示的基团等，式(A-1)新型二取代1，2，4-三嗪化合物 中，环A1为可被取代的环烷基等；RB为单环式环
Abstract:
本发明提供具有醛固酮合成酶的抑制活性、在预防及/或治疗与醛固酮相关的各种疾病或症烷基等。状方面有用的新型二取代1,2,4-三嗪化合物或其药理学上可容许的盐、其制造方法、其应用、以及将所述化合物或其药理学上可容许的盐作为有效成分而形成的医药组合物等。本发明涉及通式[I]表示的化合物或其药理学上可容许的盐，(51)Int.Cl.C07D 471/04(2006.01)C07D 471/08(2006.01)C07D 498/08(2006.01)C07D 498/10(2006.01)
Abstract(English):

The present invention provides: a novel disubstituted 1, 2, 4-triazine compound that has an aldosterone synthase inhibitory activity and is useful in the prevention and/or treatment of various diseases or symptoms involving aldosterone, or a pharmaceutically acceptable salt of said compound; a method for producing same; a use for same; and a pharmaceutical composition, etc. formed using the compound or pharmaceutically acceptable salt thereof as an active ingredient. Provided is a compound represented by general formula [I]: [In the formula, RA is a group, etc. represented by formula (A-1) (in the formula, ring A1 is an optionally substituted cycloalkyl group, etc.), and RB is a monocyclic cycloalkyl group, etc.], or a pharmaceutically acceptable salt of said compound.

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