The invention discloses a livestock and poultry feed additive and uses thereof, and belongs to the field of livestock and poultry feed additives. The invention firstly discloses a livestock and poultry feed additive, which comprises codonopsis pilosula, tuckahoe, atractylodes macrocephala koidz, licorice root, forsythia suspensa, glutamine and taurine. According to the present invention, the livestock and poultry feed additive can be used for prevention or alleviating of livestock and poultry diarrhea or virus infection; the animal experiment results show that the livestock and poultry feed additive has effects of significant weaned piglet or chick diarrhea reducing, feed conversion rate improving, animal production performance improving, anti-oxidation property, anti-virus property and immunity enhancement; and the livestock and poultry feed additive has advantages of no drug residue, no drug resistance generation, no environmental pollution, and the like.