The invention relates to a litopenaeus vannamei parent prawn feed capable of replacing a fresh and living bait, and belongs to the field of nutrients and feeds of aquatic animals. The feed comprises the following ingredients in percentage by weight: 40% of fish meal, 6% of casein, 10% of krill meal, 15% of mussel meal, 14.75% of high-gluten flour, 0.5% of cholesterol, 2% of phospholipid, 7% of fish oil, 1% of choline, 0.5% of astaxanthin, 0.75% of vitamin C, 1.5% of calcium hydrogen phosphate, 0.5% of complex vitamins, and 0.5% of composite mineral substances. According to the litopenaeus vannamei parent prawn feed disclosed by the invention, through a compounding ratio of various nutrient components and through selection of raw materials, a prepared compound feed can meet nutritional requirements of parent prawns for reproduction, and feeding effects in respects of an egg laying rate, a continuous egg laying rate, a hatching rate, a distortion rate, egg diameters and the like of the parent prawns fed with the litopenaeus vannamei parent prawn feed are not significantly different from those fed with fresh and living clamworms, so that the feed disclosed by the invention can replace the fresh and living bait for strengthening the nutrients of the parent prawns, and the problem that the parent prawns are infected with external disease sources when being fed with the fresh and living bait is solved.