中科微点-全球专利检索

  1. Login
  2. Sign Up
Invention Publication
CN106349357A 一种鹿茸多肽在影响间充质干细胞迁移中的应用 有权

一种鹿茸多肽在影响间充质干细胞迁移中的应用
Abstract:
本发明属于生物医药技术领域，公开了一种鹿茸多肽在影响间充质干细胞迁移中的应用。该发明 使 用鹿茸 多肽的 氨基酸序 列为VLSATDKTNVLAAWGKVGGNAPAFGAEALERM。浓度为0～1ug/ml的鹿茸多肽，为促进间充质干细胞的迁移；浓度为5～50ug/ml的鹿茸多肽，为抑制间充质干细胞的迁移；该应用对提高脂肪间充质干细胞向受损缺血心肌组织中的迁移能力，治疗心肌梗塞及对移植后心肌的修复至关重要。
Abstract(English):

The invention belongs to the technical field of biomedicine, and discloses application of pilose antler polypeptides to affecting migration of mesenchymal stem cells. Amino acid sequences of the pilose antler polypeptides are VLSATDKTNVLAAWGKVGGNAPAFGAEALERM. Migration of the mesenchymal stem cells can be promoted by the pilose antler polypeptides with the concentration of 0-1 ug/ml; migration of the mesenchymal stem cells can be inhibited by the pilose antler polypeptides with the concentration of 5-50 ug/ml. The application has the advantage that the application is essential for improving the migration capacity of the adipose mesenchymal stem cells towards damaged ischemic myocardial tissues, treating myocardial infarction and repairing transplanted cardiac muscles.

Public/Granted literature
Patent Agency Ranking
0/0