The invention relates to an indoor multi-export pedestrian flow simulation method giving consideration to evacuation guidance. Firstly, gridding processing is conducted on an indoor space, then pedestrian evacuation is initialized, and evacuated pedestrians are arranged in random empty cells in a uniform random distribution mode and are represented by dots different from guiders in color; then, the pedestrians in cells are searched, and the guiding action force exerted to the pedestrians, the acting forces among the pedestrians, visible export attractions and obstacle repulsion forces are parsed, and the four directions towards which the pedestrians go possibly so as to obtain a direction matrix A; finally, the direction matrix is parsed, the pedestrians participate in competition to obtain actual moving directions; the positions of the pedestrians are updated till all the pedestrians reach exports. By the adoption of the method, a pedestrian flow evacuation model based on a cellular automaton can be perfected, the inherent law between the pedestrian flow evacuation effect in a multi-export evacuation guidance scene and a guidance effect is disclosed, and a theoretical support is provided for assessment and optimization of a pedestrian flow evacuation guidance strategy.