The invention belongs to the technical field of separation membranes and relates to a columnar hollow fiber membrane module manufacturing method and a columnar hollow fiber membrane module manufacturing device. The method includes steps: manufacturing of U-shaped membrane filament bundles, to be more specific, winding hollow fiber membrane filaments to form the U-shaped membrane filament bundles in required length, wherein the head of one end of each U-shaped membrane filament bundle is bent; glue injection, to be more specific, subjecting the U-shaped membrane filament bundles to single-end (the other ends of the bent heads) glue injection to form independent pouring unit bundles; assembly, to be more specific, fixing the pouring unit bundles into membrane shells (pressure type membrane modules) or membrane frames (immersed modules); glue feeding and pouring, to be more specific, directly mounting glue injection end caps at the U-shaped ends of the bent heads of the pouring unit bundles to perform glue feeding and pouring; solidifying and cutting, to be more specific, after glue solidification, cutting glue surfaces to perforate membrane filaments, so that membrane module manufacturing is finished. The columnar hollow fiber membrane module manufacturing method and the columnar hollow fiber membrane module manufacturing device have advantages that hollow fiber membrane filament utilization rate and membrane module pouring and end sealing quality in a columnar hollow fiber membrane module manufacturing process are increased, and membrane filament blockage rate is decreased; work intensity is relieved, and efficiency improvement, cost saving, simplicity and convenience are achieved.