The invention relates to an application of a traditional Chinese medicinal composition in preparing medicines for treating senile fundus arteriosclerosis and fundus maculopathy, and belongs to the technical field of medicines. The applicant, through clinical researches and animal experiments on blood harmonizing and eyesight improving tablets, discovers that the traditional Chinese medicinal composition has a good therapeutic effect on the senile fundus arteriosclerosis in the clinical field; in a process of conducting pharmacological researches, the applicant, on the basis of the principle of adding and subtracting traditional Chinese medicines, adds radix cynanchi panicullati, herba schizonepetae and white atractylodes rhizome based on the prescription of the blood harmonizing and eyesight improving tablets, so that the therapeutic effect on the senile fundus arteriosclerosis is enhanced; the traditional Chinese medicinal composition can obviously reduce such indexes as TC, TG and the like and significantly increase HDL; and more importantly, the traditional Chinese medicinal composition has a significant difference with atorvastatin in an anti-inflammatory effect; therefore, the traditional Chinese medicinal composition has a good clinical application prospect.