The invention discloses a traditional Chinese medicine active part for preventing chronic pelvic inflammation, and a preparation method and applications thereof. The content of the traditional Chinese medicine active part is 50-90%, and the traditional Chinese medicine active part comprises the following components in percentage by weight: 8.37-16.11% of astilbin, 4.52-12.55% of neoastilbin, 6.97-15.90% of isoastilbin, 15.47-22.65% of neoisoastilbin, 15.66-24.97% of engeletin and 3.75-7.15% of gracillin. The traditional Chinese medicine active part preparation for preventing chronic pelvic inflammation is prepared by combining smilax china flavonoid compound and saponin according to certain proportions, the curative effect is definite, the active ingredients are clear, and the traditional Chinese medicine active part has the efficacies of clearing away heat and toxic materials and invigorating blood circulation to remove blood stasis, is effectively used for preventing chronic pelvic inflammation, and is safe to use, convenient to take, small in dose and good in compliance of patients.