The invention provides a multi-probe compatible in-situ projection imaging processing system. The multi-probe compatible in-situ projection imaging processing system is composed of an optical system module and an image collecting and processing module, wherein the optical system module is integrated with a plurality of groups of imaging probes, each group of imaging probes generates exciting light which irradiates the operating field, the reflection light reflected from the operating field is processed, and the processed reflection light is transmitted to the image collecting and processing module; the image collecting and processing module receives the reflection light information processed by the optical system module, and processes the reflection light information, thus the visual image of the operating field is obtained, and the visual image of the operating field is projected to the operating field at the ratio of 1 to 1 by adopting an in-situ projection technology. For the multi-probe compatible in-situ projection imaging processing system, the imaged picture is projected to the operating field, and the position of the ureter can be identified in the operating field; the plurality of imaging probes are integrated, so that the needed imaging probe can be selected according to the actual demand; the multi-probe compatible in-situ projection imaging processing system is small and exquisite as well as portable, can be conveniently held by a doctor, and is suitable for being used for navigation during the operation.