The invention discloses a brewing method of Luzhou-flavor fruity liquor, and belongs to the field of wine making. The brewing method of the Luzhou-flavor fruity liquor comprises steps of selecting fruits for brewing the liquor, pre-processing the fruits, preparing a distiller's yeast, conducting fermentation and distillation, and storing a liquor base. In the step of conducting fermentation and distillation, raw materials are fermented in a mode of being mixed with activated water, and the activated water undergoes ionization and is added with inorganic ions. The Luzhou-flavor fruity liquor brewing method provided by the invention has the characteristics that the Luzhou-flavor fruity liquor provides more choices for Baijiu from the aspect of taste, and the taste of the liquor is improved at the same time; on the basis of reserving the properties of the Luzhou-flavor liquor which is intense in pit flavor and lasting in aftertaste, the feelings of being sweet and soft and being fresh and clean in aftertaste are added for the Luzhou-flavor liquor brewing method, so that the Luzhou-flavor liquor brewing method is more abundant in taste and is popular in more consumers; and meanwhile, a preparation process is improved and the total content of formaldehyde in the liquor is reduced.