The invention discloses a high-yield cultivation method for semen cassiae. The method includes the steps that a base fertilizer is applied, and bedding is performed; a cultivation box is fixed to each furrow, each cultivation box is provided with an upper cover capable of being opened and closed, and the lower bottom face of each cultivation box is provided with a detachable protecting table; each protecting table is of a hollow structure with the two ends being opened, and furrow-shaped grooves are formed in the inner side walls of the protecting tables; each upper cover is provided with through grooves, and bar-shaped boxes are detachably arranged in the through grooves; the bar-shaped boxes are provided with circular through holes which is the same as the bottom faces of the corresponding protecting tables in size, and the upper surface of each bar-shaped box is covered with a thin film; semen cassiae seeds are sown at the bottom of each protecting table after being treated, and earthing is conducted after sowing is completed; then watering is performed, the upper covers are covered and the thin films are coated; and the thin films are removed after sowing for 5-10 days, the bar-shaped boxes are dismounted when the seedling heights are 6-8cm, the protecting tables are also dismounted when the seedling heights are 20-30cm, soil is loosened, the upper covers are removed when the seedling heights are 36-40cm, and fertilization is carried out. By means of the high-yield cultivation method for the semen cassiae, the influence on the yield and quality of the semen cassiae by plant diseases and insect pests is reduced through the protecting tables, the effect that the semen cassiae in the protecting tables can be stably adapted is guaranteed, the rate of survival is increased, and the quality is improved.