The invention relates to a method for removing an oxygen-containing organic compound impurity from an aromatic hydrocarbons material flow to mainly solve the problem that in production of an aromatic hydrocarbons reaction product from an oxygen-containing compound, poisoning of a catalyst and an adsorbent used in a production process of p-xylene is caused because a little amount of an oxygen-containing compound is contained. The method adopts the technical scheme including the following steps: 1) providing an aromatic hydrocarbons material flow including at least one of benzene, toluene, xylene, and aromatic hydrocarbons with 9 carbon atoms and carbon atoms more than 9, wherein the aromatic hydrocarbons material flow contains at least 10 ppm by mass percentage of an oxygen-containing compound; and 2) allowing the aromatic hydrocarbons material flow to pass through an oxygen-containing organic compound removal unit to remove the oxygen-containing organic compound impurity, wherein the purified aromatic hydrocarbons material flow contains the oxygen-containing organic compound impurity with the mass percentage less than 10 ppm, so that the problem above is well solved. The method can be used for industrial production of aromatic hydrocarbons made from an oxygen-containing compound.