The invention provides a machine tool machining method of a high temperature resisting heat insulation sandwich material component. The method comprises the following steps that (1) a component material blank is arranged on a machining tool; (2) locating features are used for locating the component material blank; (3) the located component material blank is fixed; and (4) the component material blank is subjected to edge cutting machining, and an edge cutting machining component is obtained. The component material blank is provided with a heterogeneous layer structure, and edge cutting machining is carried out through a machine tool machining manner. The method is simple, operation is easy and convenient, and pollution to the environment is small; the machining precision and machining efficiency of the component can be greatly improved; and the method is mainly used for the fields of the aerospace industry, the civil industry and the like.