The invention, which belongs to the system control and simulation field in aerospace propulsion theory and engineering, provides a design and dispatching method of a constraint predictive controller on various working conditions of an aero-engine. A control system has two layers. At the first layer being a flight envelope dispatching layer, a flight height and a Mach number are used as dispatching parameters; a weight of a predictive controller is distributed by using a fuzzy membership method to obtain controlled quantities under a plurality of nominal working states on a current flight condition. At the second layer being a working state dispatching layer, a rotating speed is used as a dispatching parameter; the controlled quantities obtained at the first layer are processed by using a linear interpolation method to determine a current controlled quantity on the current working condition. Therefore, flight envelope and work state area division are carried out to determine various nominal working conditions; according to a control objective of reaching an expected rotating speed of an aero-engine on the input and output constraints, corresponding constraint predictive controllers on the different working conditions are designed; with design of dual-layer dispatching logic, the constraint predictive controllers at various working conditions are coordinated, so that steady-state controlling on a non-nominal working state can be realized.