The invnetion provides a multi-point geostatistical modeling method and device. The method comprises steps that a three-dimensional training image is established according to the first deposition microphase information of a to-be-modelled region; the to-be-modelled region is divided into multiple grid nodes, ,a first grid system is established, first grid nodes having well points and second grid nodes having no well points are determined, and the second deposition microphase information of each well point is assigned to the first grid node corresponding to the each well point; a first mode database is acquired according to the grid division result of the first grid system of the to-be-modelled region, preset data template dimensions and the three-dimensional training image; all the second grid nodes are assigned; a three-dimensional geological model of the to-be-modelled region is acquired. The method is advantaged in that the deposition microphase information of each grid node of the three-dimensional geological model has excellent conformity, and conditionalization realization is easy.