The invention relates to a sensor calibration method for optical remote sensing satellite multi-CCD multi-camera unified processing. The sensor calibration method comprises the following steps: firstly taking mounting positions of CCD linear arrays of multiple cameras on an optical remote sensing satellite platform along the direction of a track as benchmark, constructing a virtual CCD linear array, and mounting the virtual CCD linear array on a center line of multiple cameras along the direction of the track; secondly, establishing a strict imaging model of a unified platform; thirdly, constructing a strict imaging model of each CCD; fourthly, for each image point on the virtual CCD linear array, according to direct transformation of the strict imaging model of the unified platform, calculating plane coordinates of a ground point of the image point, and assigning a value to the average elevation of the ground point, so that geographic coordinates of the ground point are obtained; fifthly, according to the strict imaging model of each CCD and the geographic coordinates, calculated in the step four, of the ground point, calculating image point coordinates of the image point by adopting strict imaging model inverse transformation, and assigning a value to a virtual CCD image point; and sixthly, repeating the steps four and five until processing of all the image elements on a virtual CCD is completed.