The invention provides a laser protection material, and relates to the field of an inorganic nonmetallic functional material. The laser protection material has a chemical formula of (Sm<1-x-y>YbxEry)2O2S, wherein the x is greater than or equal to 0.08 but smaller than or equal to 0.16; the y is greater than or equal to 0.005 but smaller than or equal to 0.02. The laser protection material absorbs 1.06mu m and 1.54mu m near infrared laser through Sm<3+> transition; the laser protection goal is achieved. Through the upper conversion effect of the Yb<3+> and Er<3+>, the laser protection capability of the materials is further enhanced. The invention also relates to a preparation method of the laser protection material. The method comprises the following steps of performing basic hydrolysis on Sm, Yb and Er to obtain hydrolysis products; performing reaction on the hydrolysis products in the sealed and heating first environment to obtain a first product; performing reaction on the first product, polyvinylpyrrolidone and thiourea in the sealed and heating second environment to obtain a second product. The preparation method has the advantages that the synthesis temperature is low; the operation is convenient and safe.