The invention belongs to the technical field of fuel components, and in particular relates to a fuel rod oxidation kettle which comprises an oxidation kettle body, a flange cover and an oxidation basket, wherein the oxidation kettle body takes the shape of a cylinder; the lower bottom of the oxidation kettle body is spherical; a flange is arranged at the upper end of the oxidation kettle body; the flange cover and the flange are integrally combined and connected through a plurality of studs and screw nuts and are used for sealing the oxidation kettle body; the oxidation basket is arranged inside the oxidation kettle body and is used for holding a fuel rod in oxidation. By adopting the fuel rod oxidation kettle, the problems that a conventional oxidation kettle is poor in sealing property and further high-temperature high-pressure steam generated in the oxidation kettle is leaked as the sealing surface of the oxidation kettle is easy to damage can be solved. By adopting the device provided by the invention, the times that steam inside the device is leaked from the sealing surface between the oxidation kettle and the flange cover can be greatly reduced when the oxidation kettle is in a long-term high-temperature high-pressure operation state, and thus the sealing reliability is improved. In addition, the basket is not easily clamped inside the oxidation kettle, so that product scrap can be avoided.