The invention provides a method for determining organochlorine and pyrethroid insecticide residues in an electronic cigarette liquid. The method comprises the following steps: an n-hexane and acetone mixed solution is prepared in a mass ratio being 1:1 and taken as an extraction solvent; ultrasonic extraction is performed with the solvent, a purification bag is added for centrifugation, then a supernatant is transferred to a Florisil column containing anhydrous sodium sulfate, the supernatant is eluted with the n-hexane and acetone mixed solution, and an eluent is collected and subjected to GC-mu ECD analysis. With adoption of the method, residual quantities of organochlorine and pyrethroid insecticides in the electronic cigarette liquid can be detected simultaneously, efficiently and accurately.