The invention discloses cold-mixed asphalt, and a preparation method and application thereof, belonging to the field of asphalt. Specifically, the cold-mixed asphalt provided by the invention comprises petroleum asphalt, epoxy resin, a compatilizer, an amine curing agent and an additive, wherein the compatilizer is alkylbenzene sulfonate; the additive is active carbon loaded with surface-modified inorganic nanometer particles; and a mass ratio of petroleum asphalt to epoxy resin to the compatilizer to the amine curing agent to the additive is 100: (20-40): (10-15): (5-10): (1-5), preferably 100: (25-35): (10-12): (6-8): (2-4). The cold-mixed asphalt provided by the invention can be applied at normal temperature and has good rut resistance and water stability; and the cold-mixed asphalt also has the advantage of environmental protection and shows good application prospects.