The invention discloses a quantitative detection method of syringin as an effective component in a Xuezhitong capsule and belongs to the field of quantitative detection of the effective component in the Xuezhitong capsule. The quantitative detection method of the syringin as the effective component in the Xuezhitong capsule comprises the following steps: (1) utilizing an extraction solvent to extract the syringin in the Xuezhitong capsule to be detected to obtain an extracting solution; (2) purifying the extracting solution to obtain a test sample solution; and (3) performing quantitative determination on the test sample solution by adopting high performance liquid chromatography. The quantitative detection method utilizes the high performance liquid chromatography to quantitatively detect the content of the syringin as the effective component in the Xuezhitong capsule, is high in accuracy and good in precision degree, stability and repeatability. The quantitative detection method of the syringin as the effective component in the Xuezhitong capsule is good in durability, high in specificity and has an application prospect in quality control or quality evaluation of the Xuezhitong capsule.