The invention discloses a global sequence generating method and device based on zookeeper. The method comprises the following steps: distributing a plurality of sequence generators, initializing sequences generated by the sequence generators to assign step lengths, loading factors and initial values for the sequences and setting a memory queue; acquiring distributed locks of zookeeper sequence nodes in a zookeeper distributing system; calculating step length sequence values of the zookeeper sequence nodes according to the current values and the step lengths of the zookeeper sequence nodes; releasing the distributed lock of the zookeeper sequence nodes to obtain step length sequence values which correspond to the zookeeper sequence nodes; asynchronously filling the step length sequence values into the memory queue of the sequence generator; and selecting a sequence value form the memory queue as a global sequence, and returning the global sequence. According to the technical scheme, a unique global sequence can be provided, and business requirements are met.