Described is a hinge for doors or windows comprising: a first fixed body (5) associated with a fixed frame (1) and having a first axis (X1) of fixed articulation and a slot (6) made parallel to the axis (XC) of longitudinal extension of the first fixed body (5); a second movable body (7) connected to a movable sash (2); a first lever (8) having a first end articulated to the first fixed body (5) about the first axis (X1) of fixed articulation, a second end articulated to the second movable body (7), defining a second axis (X2) of articulation, and an intermediate zone; a second lever (9) having a first end articulated inside the slot (6) of the first fixed body (5) to define a third slidable axis (X3) of articulation, a second end articulated to the second movable body (7) defining a fourth axis (X4) of articulation and an intermediate zone; the first (8) and the second (9) levers are articulated to each other in the corresponding intermediate zone to define a fifth axis (X5) of shared articulation; means (10, 11) for adjusting at least one between the first axis (X1) of articulation and the third slidable axis (X3) of articulation along at least a first horizontal axis (XR1) parallel to the axis (XC) of longitudinal extension of the first fixed body (5) or a second horizontal axis (XR2) perpendicular to the axis (XC) of longitudinal extension of the first fixed body (5); the adjustment means (10) comprising a slide (12) positioned on the first fixed body (1) and having a first constraining portion for the first axis (X1) of articulation and a second portion connected to an adjustment axis (X12), parallel to the first axis (X1) of articulation, using a rotary element (13) configured for moving the slide (12), in both directions and along the first horizontal axis (XR1), in such a way as to vary the distance (D) between the adjustment axis (X12) and the first axis (X1) of articulation along the first horizontal axis (XR1), in both directions.