The invention provides a parking lot vehicle parking guidance system, which comprises a liquid flow guidance system, a parking space judgment system and a center control management system. The liquid flow guidance system comprises guidance channels and artery valves arranged in the guidance channels, wherein the guidance channels are arranged in a parking lot; the vehicle parking judgment and processing system is used for judging whether a parking space is parked with a vehicle and transmitting the information on whether the parking space is parked with the vehicle and position information of the parking space to the center control management system; and the center control management system controls a switch of the corresponding artery valve in the corresponding guidance channel according to the position information of the available parking space to enable liquid in the guidance channel to flow to the available parking space. According to the parking lot vehicle parking guidance system, a driver can follow the liquid according to the flow direction of the liquid in the corresponding guidance channel to quickly find the empty parking space, thereby reducing overall parking time, improving parking efficiency of the driver and providing great convenience for parking of people.