The invention discloses a multipoint series connection emergency shutdown signal state monitoring circuit. N emergency shutdown buttons are in series connection sequentially; the normally-closed contact wiring terminal 1 of the first emergency shutdown button is connected with a DC power supply circuit; the normally-closed contact wiring terminal 2 of each emergency shutdown button is connected with a corresponding emergency shutdown state monitoring relay control coil through a normally-open contact of an emergency shutdown state monitoring relay; and the wiring terminal A2 of the emergency shutdown state monitoring relay control coil is connected with a DC zero wire. When an emergency shutdown fault happens in an area, through the multipoint series connection emergency shutdown signal state monitoring circuit, the emergency shutdown generated by which emergency shutdown button or which section of line in the multipoint series connection emergency shutdown line in the area can be timely known. After the emergency shutdown fault is processed, through triggering an emergency shutdown state monitoring reset button, an emergency shutdown state monitoring reset relay is electrified in a short time, and each emergency shutdown state monitoring relay in the multipoint series connection emergency shutdown signal state monitoring circuit can be in an electrified self-holding state again.