The invention discloses a composition capable of detecting multiple tumors, and the composition is used as an antibody vector to participate immune turbidity reaction, is applicable to detect multiple tumors and helps to substantially improve detection sensitivity. The composition capable of detecting multiple tumors is composed of multiple antibodies capable of identifying tumor specific antigens, a polymer and a colloidal gold solution. The preparation method for the composition comprises labeling the multiple antibodies capable of identifying tumor specific antigens respectively with colloidal gold, enables the multiple antibodies and the polymer to form a copolymer containing the multiple colloidal-gold-labeled antibodies capable of identifying tumor specific antigens, and then taking the copolymer as an antibody vector to precipitate the immune turbidity reaction. The composition is an immunity-enhanced in-vitro diagnostic reagent for detecting multiple tumors, is capable of detecting multiple tumors, possesses universal applicability, and is relatively high in detection sensitivity.