The invention relates to a forecasting and early warning system and method for mine pressure of an underground working face of a coal mine, and belongs to the field of coal mining. The forecasting andearly warning system mainly comprises a monitoring module and a forecasting and early warning module. The forecasting and early warning method comprises the steps that based on the calculating formula and the statistic law of the theory related to mine pressure, relevant information of the working face at different periods is collected and processed, the mine pressure strength of the working faceis prejudged, the position and the strength of each time of weighting are forecasted, before-mining pressure early warning before mining of the working face is achieved, and long-time early warning and real-time early warning in the mining process of the working face are achieved; and meanwhile, corresponding prevention and control measures of a high mine pressure disaster are given based on dataof large database in the background. According to the forecasting and early warning system for the mine pressure of the underground working face of the coal mine, all-time forecasting of the positionand the strength of weighting of the comprehensive mechanized working face and weighting dynamic early warning are achieved, guiding significance for support selection and prevention and control andtreatment of the high mine pressure disaster is provided, and safe and efficient exploiting of the working face is ensured.