The invention discloses a manufacturing method and application of an alveolate blind hole toughened zirconium oxide ceramic shell. The method comprises the following steps: sintering a green body at the temperature lower than the ceramic sintering temperature to obtain a biscuit, of which the particles are partially sticky, wherein the biscuit has certain strength and the density is only 85%-95% of the theoretical density; engraving a regularly polygonal blind hole or a round blind hole by a fine engraving machine; sintering again to perform densification; and filling an organic macromolecularplastic material which is solidified with epoxy resin or silica gel and the like into the blind hole. On one hand, according to the scheme, sintering processing is conducted at the temperature lowerthan the sintering temperature, processibility higher than that of an injection molding green body is achieved, higher processing efficiency and cost advantage are achieved in compared with those of sintering piece processing, and the organic macromolecular plastic material in the blind hole absorbs part of impact energy which falls off in the colliding and falling process, so that the breaking toughness of the ceramic shell is improved. On the other hand, according to the scheme, the weight of the shell can be effectively reduced, lighting and thinning of electronic products are benefited, and the alveolate blind hole toughened zirconium oxide ceramic shell can be used for preparing consumer electronic shells such as watch shells, mobile phone shells and tablet computer shells.