The invention discloses a noise reduction structure for machine tool protection. The structure is especially suitable for noise reduction of a machine tool outer protection. the noise reduction structure comprises a protective cover, wherein a cover plate is arranged on protective cover; the cover plate is fixed on the protection cover through a sound resistance body; a sealing strip is arranged between the cover plate and the protective cover; a sound-absorbing material is filled between the cover plate and the protective cover; and an air cavity is reserved between the sound absorption material and the cover plate. According to the noise reduction structure, noise of a machine tool is reduced by adopting a laminated structure, and noise transmission is effectively reduced.