The invention discloses a method for preparing 7-acetyl paclitaxel. The method comprises the following steps: 1, acetylizing the seventh position and the tenth position of 10-Dab used as a raw material to prepare an intermediate 1; 2, carrying out a condensation reaction on the intermediate 1, the side chain acid of paclitaxel and a condensation agent to prepare an intermediate 2; and 3, carryingout acid and alkali treatment on the intermediate 2 to prepare the 7-acetyl paclitaxel. The method has the advantages of mild reaction conditions, simplicity in operation, realization of massive production, and provision of convenience for further studying of the paclitaxel.