The invention, which belongs to the technical field of uranium ore geological research, specifically discloses a prediction method of a favorable sand body and a favorable zone of sandstone type uranium ore. The method comprises the following steps: step 1, carrying out ancient landform restoration; step 2, carrying out ancient landform division; and step 3, predicting a favorable sand body and afavorable zone of uranium ore. With the method provided by the invention, the favorable zone of the sandstone type uranium ore is determined by restoring an ancient landform of the ore target stratumdepositional stage and the uranium ore formation key period.