High voltage high power pulsed power switches relating to a laser triggered multi-stage vacuum switch. The laser triggered multi-stage vacuum switch has laser triggered vacuum gap, multi-stage self-breakdown vacuum gaps and trigger system. Multi-stage self-breakdown vacuum gaps are fixed on the top of laser triggered vacuum gap by connector. The grading ring is sheathed outside of upper insulation shell. By adopting the series connected laser triggered vacuum gap and multi-stage self-breakdown vacuum gaps, with the synergy of two type vacuum gaps, application of laser triggered multi-stage vacuum switch in the high voltage, high power, high repetitive frequency pulsed power system can be realized. With multiple laser beams shot onto multiple targets, more initial plasma can be generated as the irradiation area of laser on target surfaces is enlarged, and the trigger performances of laser triggered multi-stage vacuum switch can be enhanced.