The invention provides a method for multiplying cymbidium hybridum seedlings effectively by utilizing shoot tip tissues. The method comprises the following steps: selection of explants; lateral bud disinfection; protocorm inducing culture; protocorm multiplication culture; protocorm differentiation culture and rooting and hardening-off culture. The method has the advantages that the inductivity of protocorms is improved in the inducing stage; the aberration rate and the vitrification ratio of the protocorms are reduced in the multiplication stage; the bud variation ratio is reduced in the differentiation stage; in the rooting and hardening-off stage, the growth and the development of the seedlings are better, the twisting ratio of new roots is low, the roots are more disperse and stretch out better, and the seedling aberration rate is reduced.