The embodiment of the invention discloses a control method and device of a screen virtual mask in terminal equipment and the terminal equipment. The method includes the following steps that a program,running at present, of a system and the running state of the program are detected; according to the program, running at present, of the system and the running state of the program, whether hidden conditions are satisfied or not is met; when the hidden conditions are satisfied, the virtual mask is hidden, and the hidden conditions include the followings that the program, running at present, of thesystem includes a first preset program, and the running state of the first preset program is displayed on the foreground of a screen. According to the embodiment, the problems that when a user uses the virtual mask to protect the eyes, the user needs to perform additional operation frequently to operate the equipment and the user's use experience is seriously affected are solved, the user operation is simplified, and the intelligent control of the virtual mask is improved.