The invention discloses an anti-fungal multifunctional makeup brush. Except for the brush, other parts are prepared through injection moulding by using anti-fungal plastic; the brush comprises a brushhandle, a brush head installed on the head of the brush handle, a first combination brush and a second combination brush, the first combination brush and the second combination brush each comprises asleeve type brush handle and a brush body arranged on the head of the sleeve type brush handle, the sleeve type brush handle of the first combination brush sleeves the brush head, and the sleeve typebrush handle of the second combination brush sleeves the sleeve type brush handle of the first combination brush. The makeup brush has the advantages that three different makeup brushes are combinedinto a whole, three different kinds of makeup purposes are achieved, use is more convenient, carrying and storing are better facilitated, the production cost of a factory and the use cost of a consumer are lowered, and meanwhile the multifunctional makeup brush is not likely to be mildewed under the wet condition, and the service life is prolonged.