The invention relates to a synthesis method of a novel complex for drug testing, in particular to a Pb-containing complex Pb(bpbp)3(NO3)2, wherein bpbp represents 2,6-bis(2-(1-phenyl)benzimidazole)pyridine. The invention further relates to a crystal structure of the complex. The preparation method is simple and fast, and the complex is low in toxicity and high in yield. Compared with a conventional crystal culture method of the ligand complexes, the method has the advantages that solvents for synthesis are water and methanol, and a large quantity of crystals can be obtained in three days. Withadoption of a fluorescence analysis method, a fluorescence spectrum of interaction of a target product and BSA (bovine serum albumin) is tested; the fluorescence quenching phenomenon of BSA indicatesthat the complex has stronger interaction with BSA, so that the complex can be applied to biological drug detection.