The invention discloses a tail door limiting device and a vehicle with the tail door limiting device. The tail door limiting device comprises a limiting base and a limiter. The limiting base is arranged on a side body of the vehicle and provided with a limiting base matching face. The limiter is arranged on a tail door inner plate of the vehicle. The limiter comprises a base, a limiting block anda positioning piece. The limiting block is provided with a limiting block matching face opposite to the limiting base matching face. The limiting block is arranged in the manner that the position relative to the limiting base matching face is adjustable, and accordingly the limiting block limiting face gets close to or gets away from the limiting base matching face. The positioning piece is used for positioning the adjusted limiting block on the base. According to the tail door limiting device of the embodiment, after the limiting block and the limiting base are installed, the distance betweenthe limiting block and the limiting base can be adjusted, and accordingly when a tail door of the vehicle is closed, it can be guaranteed that the tail door is fixed relative to the side body of thevehicle, and it can also be guaranteed that the tail door has proper door closing strength.