Disclosed are a PC/ABS composition, a preparation method therefor and the use thereof. The composition comprises the components of: 60-70 parts of a polycarbonate resin; 30-40 parts of an acrylonitrile-butadiene-styrene copolymer; and 0.5-5 parts of a compatilizer, wherein the polycarbonate resin is a bisphenol A-type polycarbonate having a melt mass flow rate (MFR) of 8 g/10 min to 10 g/10 min at 300ºC under a load of 5 kg; and the acrylonitrile-butadiene-styrene resin has a melt mass flow rate (MFR) of 15 g/10 min to 20 g/10 min at 220ºC under a load of 10 kg. In the present invention, a nanoscale bicontinuous phase structure can be obtained by selecting and controlling the PC/ABS ratio and matching the viscosities of PC and ABS, the high-speed impact resistance of a material can be effectively improved, multi-axis impact is presented as a ductile fracture, the safety of use is improved, and the prepared PC/ABS composition has a good toughness and safety during high-speed impact while ensuring the rigidity of the material, and can be widely applied to the preparation of interior automobile parts.