The invention relates to a multi-beam data edge matching processing method for different blocks. The method includes the workflow and steps of (1) conducting meshing processing on data of a block A and data of a block B separately; (2) extracting cross sections of the block A and block B at the same position in the middle of an overlapping area in step (1) respectively to obtain water depth values; (3) deleting the overlapped data in all areas by using the cross sections extracted in step (2) as boundaries; (4) calculating a water depth difference value h of the same point of the two extractedcross sections; (5) in combination with a regional water depth observation value Z0, using a trend surface calculation process to obtain a block water depth correction value Z. By conducting edge matching processing on the data of different blocks, the accuracy of multi-beam depth measuring data can be improved, and the problems that the terrain trend is uncoordinated and the depth contour line trend is abnormal when the multi-beam data is subjected to edge matching can be well solved.